Carolina Sardinha Francisco

Position: Postdoc

Office: 502


Research Interests

I am interested in the regulatory circuits controlling pathogen adaptation and cellular responses during environmental stresses and host infection. In Eva Stukenbrock’s lab, we use as model system Zymoseptoria tritici, the most damaging fungus in worldwide wheat crops and an emerging model organism due to its striking morphological adaptation.

It has been recently described that extracellular vesicles carry a variety of molecular cargo with an essential role in fungal development and host-pathogen interactions. Therefore, my postdoc project aims to decipher the differential extracellular vesicle content among different Z. tritici strains which may play a role in their overall fitness.

Short CV

2020 – Present

Postdoc in the group of Eva Stukenbrock, Environmental Genomics at Christian-Albrechts University, Kiel, Germany

2015 – 2020 

PhD student in the group of Bruce A. McDonald, Plant Pathology at Swiss Federal Institute of Technology (ETH), Zürich, Switzerland

2012 – 2014 

Master student in Genetics and Plant Breeding, University of São Paulo (UNESP) & Citrus Research Institute ‘Sylvio Moreira’ (IAC), São Paulo, Brazil

2007 – 2010 

Bachelor of Science in Biology, Fundação Herminio Ometto (FHO), São Paulo, Brazil


Dutta, A., Hartmann, F.E., Francisco, C.S., McDonald, B.A., and Croll, D. 2021. Mapping the adaptative landscape of a major agricultural pathogen reveals evolutionary constraints across heterogeneous environments. The ISME Journal,

Francisco C.S., Zwyssig, M.M., and Palma-Guerrero, J. 2020. The role of vegetative cell fusions in the development and asexual reproduction of the wheat fungal pathogen Zymoseptoria tritici. BMC Biology, 18(1), 1-16. 

Fouché, S., Badet, T., Oggenguss, U., Plissonneau, C., Francisco, C.S., and Croll, D. 2020. Stress-driven transposable element de-repression dynamics and virulence evolution in a fungal pathogen. Molecular Biology and Evolutions, 37 (1), 221-239.

Francisco C.S., Ma, X., Zwyssig, M.M., McDonald, B.A., and Palma-Guerrero, J. 2019. Morphological changes in response to environmental stresses in the fungal plant pathogen Zymoseptoria tritici. Scientific Reports, 9(1), 1-18.

De Paula, L.B., Lin, H., Stuchi, E.S., Francisco, C.S., Safady, N.G., Coletta-Filho, H.D. 2019. Genetic diversity of Candidatus Liberibacter asiaticus in Brazil analyzed in different geographic regions and citrus varieties. European Journal of Plant Pathogen, 154(4), 863-872.

Safady, N.G., Lopes, J.R.S., Francisco C.S., and Coletta-Filho H.D. 2019. Distribution and genetic diversity of Xylella fastidiosa subsp. pauca associated with olive Quick Syndrome symptoms in Southeastern Brazil. Phytopathology, 109 (2), 257-264.

Francisco C.S., Ceresini P.C., Almeida R.P.P, and Coletta-Filho H.D. 2017. Spatial genetic structure of coffee-associated Xylella fastidiosa populations indicates that cross infection does not occur with sympatric citrus orchards. Phytopathology, 107 (4), 395-402.

Palma-Guerrero, J., Ma, X., Torriani, S.T.T., Zala, M., Francisco C.S., Hartmann, F. E., Croll, D., and McDonald, B.A. 2017. Comparative transcriptome analyses in Zymoseptoria tritici reveal significant differences in gene expression among strains during plant infection. Molecular Plant-Microbe Interactions, 30 (3), 231-244. 

Coletta-Filho H.D., Francisco C.S., Lopes, J.R.S., Muller, C., and Almeida R.P.P. 2017. Homologous recombination and Xylella fastidiosa host-pathogen associations in South America. Phytopathology, 107 (3), 305-312.

Coletta-Filho H.D., Francisco C.S., Lopes, J.R.S., de Oliveira, A.F., and da Silva, L.F.O. 2016. First report of olive scorch in Brazil associated with Xylella fastidiosa subsp. pauca. Phytopathologia Mediterranea, 130-135.

Coletta-Filho H.D., Francisco C.S., and Almeida R.P.P. 2014. Temporal and spatial scaling of the genetic structure of a vector-borne plant pathogen. Phytopathology, 104(2), 120-125.

Mafra, V., Martins, P.K., Francisco, C.S., Ribeiro-Alves, M., Freitas-Astua, J., and Machado, M.A. 2013. Candidatus Liberibacter americanus induces significant reprogramming of the transcriptome of the susceptible citrus genotype. BMC Genomics, 14(1), 247.

© Stukenbrock Lab 2018-2020