![Michael2](../_Media/michael2-2_med_hr.jpeg)
Office: 3.004
Office phone: +49 431 880 6361
E-mail: mhabig[a]bot.uni-kiel.de
Short CV
06/2014- still
Project manager in the
Environmental Genomics group: Focus on the functional characterization
of accessory chromosomes and candidate genes in Z. tritici.
10/2010-05/2014
Project manager and manager of the R&D department at IBL International GmbH, Hamburg, Germany
06/2008-09/2010
Scientist/Labhead at Bayer Technology Services GmbH, Leverkusen, Germany
11/2004-05/2008
Scientist at Novartis Institutes for BioMedical Research, Basel, Switzerland
05/2001-10/2004
Scientist at amaxa GmbH, Cologne, Germany
Publications
Habig, M. Lorrain, C. Feurtey, A. Komluski, J. and Stukenbrock, E.H. (2021) Epigenetic modifications affect the rate of spontaneous mutations in a pathogenic fungus. Nature communications, 12, 1–13.
Habig, M. Schotanus, K. Hufnagel, K. Happel, P. and Stukenbrock, E.H. (2021) Ago1 Affects the Virulence of the Fungal Plant Pathogen Zymoseptoria tritici. Genes, 12, 1011.
Möller, M. Habig, M. Lorrain, C. Feurtey, A. Haueisen, J. Fagundes, W.C. Alizadeh, A. Freitag, M. and Stukenbrock, E.H. (2021) Recent loss of the Dim2 DNA methyltransferase decreases mutation rate in repeats and changes evolutionary trajectory in a fungal pathogen. PLoS Genet, 17, e1009448.
Feurtey, A. Lorrain, C. Croll, D. Eschenbrenner, C. Freitag, M. Habig, M. Haueisen, J. Möller, M. Schotanus, K. and Stukenbrock, E.H. (2020) Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria. BMC genomics, 21, 1–15.
Gruner K, Esser T, Acevedo-Garcia J, Freh M, Habig M, Strugala R, Stukenbrock E, Schaffrath U, Panstruga R. 2020. Evidence for Allele-Specific Levels of Enhanced Susceptibility of Wheat mlo Mutants to the Hemibiotrophic Fungal Pathogen Magnaporthe oryzae pv. Triticum. Genes (Basel) 11:517. doi:10.3390/genes11050517.
Habig, M. and Stukenbrock, E.H. (2020) 2 Origin, Function, and Transmission of Accessory Chromosomes. The Mycota - Genetics and Biotechnology, pp. 25–47. : Springer.
Habig M, Bahena-Garrido S, Barkmann F, Haueisen J, Stukenbrock EH (2019) The transcription factor Zt107320 affects the dimorphic switch, growth and virulence of the fungal wheat pathogen Zymoseptoria tritici. Mol. Plant Pathol. doi:10.1111/mpp.12886 .
Habig M, Kema G, Holtgrewe Stukenbrock E (2018) Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus. Elife 7. doi: 10.7554/eLife.40251
Möller M, Habig M, Freitag M, Stukenbrock EH (2018) Extraordinary Genome Instability and Widespread Chromosome Rearrangements During Vegetative Growth. Genetics 210:517–529. doi: 10.1534/genetics.118.301050
Habig M, Quade J, Stukenbrock EH (2017) Forward Genetics Approach Reveals Host Genotype-Dependent Importance of Accessory Chromosomes in the Fungal Wheat Pathogen Zymoseptoria tritici. MBio 8:e01919-17. doi: 10.1128/mBio.01919-17
Dieβel E, Dorn I, Habig M, Küster M, Ochmann K (2015) Apparatus for automatically performing analyses Patent: EP2335078.
Müller-Hartmann H, Habig M (2012) Container and device for generating electric fields in different chambers. Patent: EP04006058.4
Boehnisch C, Wong D, Habig M, Isermann K, Michiels NK, Roeder T, May RC, Schulenburg H (2011) Protist-type lysozymes of the nematode Caenorhabditis elegans contribute to resistance against pathogenic Bacillus thuringiensis. PLoS ONE 6:e24619. doi: 10.1371/journal.pone.0024619
Mueller-Hartmann H, Habig M (2010) Method for treating small volumes with electrical current. Patent: EP05014758
Müller-Hartmann H, Habig M, Hoffmann P, Siebenkotten G (2010) Container with at least one electrode. Patent: EP1476537
Habig M, Blechschmidt A, Dressler S, Hess B, Patel V, Billich A, Ostermeier C, Beer D, Klumpp M (2009) Efficient elimination of nonstoichiometric enzyme inhibitors from HTS hit lists. J Biomol Screen 14:679–689. doi: 10.1177/1087057109336586
Graf C, Klumpp M, Habig M, Rovina P, Billich A, Baumruker T, Oberhauser B, Bornancin F (2008) Targeting ceramide metabolism with a potent and specific ceramide kinase inhibitor. Mol Pharmacol 74:925–932. doi: 10.1124/mol.108.048652
Habig M, Smola H, Dole VS, Derynck R, Pfister H, Smola-Hess S (2006) E7 proteins from high- and low-risk human papillomaviruses bind to TGF-beta-regulated Smad proteins and inhibit their transcriptional activity. Arch Virol 151:1961–1972. doi: 10.1007/s00705-006-0768-1
Schulenburg JH von der, Habig M, Sloggett JJ, Webberley KM, Bertrand D, Hurst GD, Majerus ME (2001) Incidence of male-killing Rickettsia spp. (alpha-proteobacteria) in the ten-spot ladybird beetle Adalia decempunctata L. (Coleoptera: Coccinellidae). Appl Environ Microbiol 67:270–277. doi: 10.1128/AEM.67.1.270-277.2001